Research

CURE2MILL, a program to improve leukemia treatment

CURE2MILL, a program to improve leukemia treatment

CURE2MILL, a program to improve leukemia treatment

CURE2MILL is a research program aimed at improving the treatment of children affected by the most severe forms of acute lymphoblastic leukemia. About Childhood Leukemias Childhood leukemia is similar to adult leukemia but can present certain differences. Acute leukemia is a type of cancer characterized by the spread of cancerous cells originating from the bone […]

DIGITWINS, the program to better understand neuroblastoma

DIGITWINS, the program to better understand neuroblastoma

DIGITWINS, the program to better understand neuroblastoma

DIGITWINS is a research program funded by Imagine for Margo, aimed at gaining a better understanding of high-risk neuroblastoma using artificial intelligence. About Childhood Neuroblastoma Neuroblastoma is an extracranial malignant tumor that develops from primitive nerve cells called neuroblasts, which normally form nerve cells in the body. This type of solid tumor is one of […]

BT4ChildLC, the research program against childhood liver cancer

BT4ChildLC, the research program against childhood liver cancer

BT4ChildLC, the research program against childhood liver cancer

BT4ChildLC is a research program aimed at identifying predictive biomarkers and new therapies to fight childhood and adolescent liver cancer more effectively. About Pediatric Liver Cancer In children, malignant tumors originating in the liver are rare, accounting for 1% of pediatric cancers. In 90% of cases, these are either hepatoblastomas (HB, 2/3) or hepatocarcinomas (HCC, […]

HEM-iSMART, a clinical trial for better treatment of leukemia and lymphoma

HEM-iSMART, a clinical trial for better treatment of leukemia and lymphoma

HEM-iSMART, a clinical trial for better treatment of leukemia and lymphoma

HEM-iSMART is an international clinical trial, co-funded by Imagine for Margo, aimed at improving the treatment of refractory pediatric malignant leukemia and lymphoma. Childhood Leukemias Leukemia in children is similar to that in adults but can have certain peculiarities. Acute leukemia is a type of cancer characterized by the spread of cancerous cells originating from […]

NEWTargets, a research program to find a better cure for Ewing’s sarcoma

NEWTargets, a research program to find a better cure for Ewing’s sarcoma

NEWTargets, a research program to find a better cure for Ewing’s sarcoma

NEWTargets is a research program aimed at using immunotherapy to target neoproteins specific to Ewing’s sarcoma, in order to cure children and adolescents suffering from this type of disease more effectively. Childhood Sarcomas Ewing sarcoma is the second most common malignant bone tumor after osteosarcoma in adolescents and young adults. Ewing sarcoma affects approximately 80 […]

PG-AML, the personalized treatment program for children with myeloid leukemia

PG-AML, the personalized treatment program for children with myeloid leukemia

PG-AML, the personalized treatment program for children with myeloid leukemia

PG-AML is a genomic analysis research program designed to personalize treatment for children with myeloid leukemia. Acute Myeloid Leukemia in Children Acute myeloid leukemia (AML) is a cancer of the blood and bone marrow. AML is the second most common leukemia in children after acute lymphoblastic leukemia (ALL). Approximately 80 children in France are diagnosed […]

Neuroblastoma relapse prevention research program

Neuroblastoma relapse prevention research program

Neuroblastoma relapse prevention research program

Research program led by Prof. Rogier Versteeg on combinatorial therapy to prevent fatal relapses in pediatric neuroblastoma. Neuroblastomas in Children A neuroblastoma is an extracerebral malignant tumor that develops from primitive nerve cells, called neuroblasts, which normally form the nerve cells of the body. This type of solid tumor is one of the most common […]

ATG4TALL: a preclinical platform to fight leukemia

ATG4TALL: a preclinical platform to fight leukemia

ATG4TALL: a preclinical platform to fight leukemia

ATG4TALL is a preclinical platform for testing new drugs for T-cell acute lymphoblastic leukemia. Childhood Leukemia Childhood leukemia is similar to adult leukemia but can present certain peculiarities. Acute leukemia is a type of cancer characterized by the spread of cancerous cells from bone marrow stem cells. These cells multiply chaotically, invade the bone marrow, […]