MOLECULAR AND IMMUNOLOGICAL ANALYSIS OF HIGH RISK TUMORS AND LEUKEMIA AT DIAGNOSIS
This trial was co-financed with the Children without Cancer race of 2016
MICCHADO – Molecular and Immunological Characterisation of High risk Childhood Cancer at Diagnosis
The MICCHADO project of the SFCE aims at enabling a complete molecular analysis and an immunologic evaluation upon diagnosis, for 600 children and teenagers with high risk cancer, thanks to advanced technologies, including high speed sequencing. Changes of these profiles during the treatment and the follow-up might be searched for thanks to blood sampling (search for the tumor circulating DNA). This project shall enable a better understanding of mechanisms of failure and resistance to first-rank treatments. In cooperation with other current projects, the results of these precise analyses shall enable to orientate much faster onto therapeutic strategies.
Promotor: Curie Institute
Main investigator: Dr Gudrun Schleiermacher
Program duration: 2018 – 2024 (3 years of recruitment, 3 years of follow up)
Planned enrollment: objective of 600 patients
Countries involved: France
Funding by Imagine for Margo: 1 200 000€
Doctor Gudrun Schleiermacher speaks about the program :
